To add to what Zorlon said in MAME GUI forks like MAME Plus and MAME PPK you can have separate rom/CHD directories so you can keep them organized and tidy.
To add to what Zorlon said in MAME GUI forks like MAME Plus and MAME PPK you can have separate rom/CHD directories so you can keep them organized and tidy.
THE BEST METHOD to run PSX games (and everything else for that matter) is via Retroarch - http://buildbot.libretro.com/nightly/
If you have any questions on how to set it up on Windows please feel free to ask, its very easy.